By train
By train
Amtrak, (http://www.amtrak.com). Amtrak's Empire Builder service, which runs between Chicago and Seattle/Portland, stops in Winona. The train station is located at 65 East Mark Street.
By car
By car
If you are travelling by car, from the north Twin Cities, travel along the Mississippi River on US highway 61 through the picturesque Hiawatha Valley. About 110 miles from the Twin Cities. From the west Rochester, take Interstate 90 east about 45 miles, then head north on state highway 43 about 6 miles. From the east La Crosse, Madison, take Interstate 90 west about 10 miles into Minnesota then continue north on US highway 61, another 15 miles.